samedi 19 septembre 2015

Jacob, Lwoff et Monod, fondateurs de la biologie moléculaire

Nobel 50 years. Jacob, Lwoff, and Monod founders of molecular biology

International conference

Organizing committee: Henri Buc, Aude Cambon, Jean-François Chambon, François Gros, Simon Legendre, Laurent Loison, Michel Morange, Maxime Schwartz, Agnes Ullmann, Moshe Yaniv.

Dates: Monday 28 and Tuesday 29, September 2015.

Place: Main lecture hall, Duclaux building, Pasteur Institute, Paris, France.

Day 1 (Monday, 28-09-2015)

9h00 – 9h15 Opening – Christian Bréchot (Director of the Pasteur Institute)

Session 1 Historical roots
Chair : Agnes Ullmann (Pasteur Institute, Paris)

9H15 – 9h55 Richard Burian (Virginia Tech, Blacksburg, USA) & Jean Gayon (Paris-1, IHPST): “Eugène Wollman and the question of lysogeny”

9h55 – 10h35 Maxime Schwartz (Pasteur Institute, Paris): “From enzymatic adaptation to the operon”


11h05 – 11h45 Laurent Loison (Centre Cavaillès, ENS, Paris): “Lwoff’s ‘microbial physiology’ and the birth of the operon model”

11h45 – 12h25 François Gros (Pasteur Institute & Collège de France, Paris): “The context of the ‘great collaboration’”


Session 2 Scientific legacy
Chair: Jean-Pierre Changeux (Pasteur Institute & Collège de France, Paris)

14h30 – 15h10 Michel Morange (Centre Cavaillès, ENS, Paris): “The oppositions to the operon model”

15h10 – 15h50 Eric H. Davidson (California Institute of Technology, Pasadena, USA): “An alternative to the operon”


16h20 – 17h00 Henri Buc (Pasteur Institute, Paris): “Cross-talks between molecular biology and evolutionary prospects in Monod and Jacob”

17h00 – 17h40 Denis Thieffry (CSB group, ENS, Paris): “The operon and systems biology”

18h00 Reception/Cocktail at the Pasteur Institute

Day 2 (Tuesday, 29-09-2015)

Session 3 Philosophical context and political commitments
Chair: Claude Debru (ENS, Paris)

9h00 – 9h40 Sean B. Carroll (University of Wisconsin-Madison, USA): “Brave Genius: Jacques Monod’s Adventures from the French Resistance to the Nobel Prize”

9h40 – 10h20 Hans-Jörg Rheinberger (Max Planck Institute, Berlin): “Structuralism, information and linguistic in the context of the operon model”


10h50 – 11h30 Anne Fagot-Largeault (Collège de France, Paris): “The responsability of the scientist”

Session 4 Pasteurian lines of research, past and present
Chair: Moshe Yaniv (Pasteur Institute, Paris)

11h30 – 12h30 Binomial 1: Jonathan Beckwith (Harvard Medical School, Boston, USA) & Jean-Marc Ghigo (Pasteur Institute, Paris)


14h00 – 15h00 Binomial 2: Julian Davies (University of British Columbia, Vancouver, Canada) & Hilde De Reuse (Pasteur Institute, Paris)

15h00 – 16h00 Binomial 3: Edmond H. Fischer (University of Washington, Seattle, USA) & Pierre-Jean Corringer (Pasteur Institute, Paris)

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